ABSTRACT

This study looked at the association between serotonin transporter gene variants and with chronic persistent tension-type facial pain. Known as triallelic 5-HTTLPR, the serotonin transporter gene-linked polymorphic region and its rs25531 polymorphism have been linked to alterations in pain perception.

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Patients often present to otolaryngologists with chronic facial pain, presumed to be of sinus origin despite normal nasal endoscopy and sinus CT. This pain has increasingly been recognized as being of neurological origin with one of the commonest underlying causes being mid-facial segmental tension-type pain (MFP) which is a version of tension-type headache affecting the mid-face.

Published in Resources

Patients often present to otolaryngologists with facial pain which has been ascribed to sinusitis in spite of normal nasal endoscopy and sinus CT. This pain has increasingly been recognized as being of neurological origin.

Published in Resources